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更新于：2026-08-23
Calcium Acetate
醋酸钙
更新于：2026-08-23
概要
基本信息
药物类型 小分子化药 |
别名 Acetate of lime、Brown acetate of lime、Calcium acetate (USP) + [13] |
作用方式 调节剂 |
作用机制 Phosphates 调节剂(磷酸盐 调节剂) |
在研适应症- |
在研机构- |
权益机构- |
最高研发阶段批准上市 |
首次获批日期 美国 (1990-12-10), |
最高研发阶段(中国)批准上市 |
特殊审评孤儿药 (美国) |
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结构/序列
分子式C4H8CaO4 |
InChIKeyWGTHSEQMDUDZLL-UHFFFAOYSA-N |
CAS号62-54-4 |
关联
19
项与 醋酸钙 相关的临床试验IRCT20160306026938N18
Investigation of the clinical effect of administering oral drops containing cinnamon, ginger and lime juice in obese patients (phase 2A)
CTR20230498
一项在健康受试者中评价含钙的磷结合剂醋酸钙片和非含钙的磷结合剂碳酸司维拉姆片对德度司他片的药动学影响的单中心、随机、开放、三周期交叉的I期临床研究
ChiCTR2300072509
A Single-Site, Randomized, Open-Label, Three-Cycle-Crossover Phase I Clinical Study to Evaluate the Pharmacokinetics of the Calcium-containing Phosphate Binder Calcium Acetate Tablets and the Non-calcium-containing Phosphate Binder Sevelamer Carbonate Tablets on Desidustat Tablets in Healthy Subjects
100 项与 醋酸钙 相关的临床结果
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100 项与 醋酸钙 相关的转化医学
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100 项与 醋酸钙 相关的专利（医药）
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157,865
项与 醋酸钙 相关的文献（医药）2026-07-29JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY
Adsorption of total phosphorus through polymeric filter media to improve the quality of effluent of UASB reactor
作者: Shaban A. Darwish ; R. P. Tiwari ; Santosh Kumar ; Anurag Tiwari ; A. R. Quaff ; Ashish Tiwari ; Shabbir Muhammad
This study investigated the adsorption of total phosphorus (TP) using a fixed-bed column filled with polymeric filter media (PFM) made from chitosan-agarose cryogels.The column, 200 mm in length with an inner diameter of 20 mm, was packed with PFMs at varying bed heights of 100, 150, and 200 mm.The effluent from a UASB reactor, containing total phosphorus impurities (TP, 16 ± 0.6 mg/L), was passed through the column at these bed heights.A peristaltic pump regulated the flow rates between 100 and 500 mL/h, ensuring consistent flow through the PFM.The post-treatment of the UASB reactor effluent was most effective at a flow rate of 100 mL/h and a bed height of 200 mm, where a breakthrough time was extended, and the initial TP removal efficiency reached 87 ± 5.5% during the first hour, gradually decreasing over time.Kinetic anal. using the Thomas and Yoon-Nelson models demonstrated a good fit with the exptl. data, both models showing strong correlation coefficients (R2 > 0.8).
2026-06-18NATURAL PRODUCT RESEARCH
Bio-standardization and development of a unique polyherbal formulation with dipeptidyl peptidase -IV inhibitory activity for type 2 diabetes mellitus
Article
作者: Durgaprasad Tiwari, Devkumar ; Dhanawane, Ujwala ; Mohanty, Ipseeta Ray
Medicinal herbs may provide an alternative source of Dipeptidyl peptidase -IV (DPP-IV) Inhibitors, particularly in light of mounting evidence of high costs and adverse drug reactions associated with synthetic DPP-IV Inhibitors. DPP-IV inhibitory activity of medicinal plants Commiphora mukul, Terminalia arjuna and Phyllanthus emblica was elucidated in previous investigations from our lab. The goal of this work was to develop a polyherbal tablet including these medicinal plants with DPP-IV inhibitory action, conduct bio-standardization investigations, and test its anti-diabetic benefits in the streptozotocin model of Type 2 diabetes. A high-performance thin-layer chromatography technique was developed and validated in terms of linearity, accuracy, precision, repeatability, the limit of detection, and the limit of quantification for the bio-standardization of polyherbal combinations. Polyherbal combination's demonstrated significant DPP-IV inhibitory activity. It was interesting to note that in the Type II diabetes experimental model, the polyherbal combination showed antidiabetic efficacy equivalent to that of the synthetic DPP-IV inhibitor Vildagliptin, which is used in clinical settings.
2026-06-01JOURNAL OF SOLID STATE ELECTROCHEMISTRY
Impact of pH on ethanol electro-oxidation in seawater-like electrolytes: implications for ocean-based mitigation strategies
作者: Tremiliosi-Filho, Germano ; V. de B. Ferraz, Thiago ; Varela, Hamilton
Abstract: This study investigates the electro-oxidation of ethanol in seawater-like electrolytes with adjusted pH, exploring its potential for CO2 mitigation strategies.Using a polycrystalline platinum bead as a model catalyst in a conventional three-electrode cell, we demonstrate that pH adjustment significantly influences electrochem. performance, with higher oxidation current densities observed at more alk. pH values.At pH 12, usable current densities for ethanol oxidation were achieved, attributed to the decreased surface coverage of Cl- ions and increased ethoxy ion concentrations, consistent with observations from similar systems in the literature.However, mass transport limitations emerged at higher potential scan rates, evident from the inversion in peak current densities between pH 13 and pH 14 compared to lower scan rates.Addnl., voltammetric profiles indicated a preference for certain platinum crystallog. faces due to variations in chloride and sulfate binding strength.Notably, potential oscillations, not previously reported under such elevated Cl- concentrations, further support these findings.Tafel anal. in the high potential region (> 1.2 V) revealed that the platinum oxide surface does not become more sensitive to ethanol oxidation with increasing pH.These insights provide an initial understanding of the main opportunities and challenges in studying and applying such systems.
100 项与 醋酸钙 相关的药物交易
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研发状态
10 条最早获批的记录, 后查看更多信息
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| 适应症 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|
| 终末期肾脏病 | 美国 | 2001-04-02 | |
| 终末期肾脏病 | 美国 | 2001-04-02 | |
| 高磷血症 | 美国 | 1990-12-10 | |
| 高磷血症 | 美国 | 1990-12-10 |
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临床结果
临床结果
适应症
分期
评价
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临床4期 | 44 | (TPOXX: Oral Antiviral) | 積選積觸鏇製憲鬱齋艱(顧窪鑰壓範膚糧鏇觸遞) = 憲淵襯築鑰壓積選壓夢 廠積鹽獵醖齋衊積繭憲 (廠餘構構鏇齋範膚積蓋, 39.6) 更多 | - | 2024-10-09 | ||
(TPOXX: Oral Antiviral and Sevelamer Carbonate) | 願糧繭獵淵鹽鏇構鑰蓋(膚簾築顧餘網製遞鏇鬱) = 衊構遞繭齋鬱壓鬱蓋鹽 齋鏇壓製範淵獵遞醖選 (獵鹹網鬱襯窪壓壓鹽選, 艱願簾繭淵醖衊艱構蓋 ~ 糧構鹽積遞衊餘鹽艱鬱) 更多 | ||||||
临床4期 | 38 | 願齋鹹廠鑰壓繭鬱窪醖(鹽鹹艱膚夢夢醖築醖壓) = 窪齋獵餘繭鑰觸範鏇壓 鑰範艱積製觸廠網餘醖 (製網願築獵夢選獵窪繭, 0.93) 更多 | - | 2016-01-14 | |||
临床4期 | 100 | Sevelamer | 繭壓糧壓餘獵築鑰觸鬱(壓觸築鹹窪壓膚遞蓋顧) = 餘廠艱鑰餘簾窪夢醖夢 構築願齋衊遞蓋窪顧襯 (遞顧網壓膚選積衊顧醖 ) | - | 2012-02-01 | ||
繭壓糧壓餘獵築鑰觸鬱(壓觸築鹹窪壓膚遞蓋顧) = 簾鹽齋積糧衊選築簾鬱 構築願齋衊遞蓋窪顧襯 (遞顧網壓膚選積衊顧醖 ) | |||||||
临床3期 | 110 | 齋襯獵築廠齋夢壓餘遞(夢窪艱鹽網構願蓋選觸) = 繭構簾憲齋鹽鬱積鑰顧 餘醖窪鏇選艱夢襯遞遞 (襯鏇窪壓鬱顧夢蓋襯範 ) | 积极 | 2011-02-16 | |||
Placebo | 齋襯獵築廠齋夢壓餘遞(夢窪艱鹽網構願蓋選觸) = 簾獵憲壓廠製遞鏇鬱膚 餘醖窪鏇選艱夢襯遞遞 (襯鏇窪壓鬱顧夢蓋襯範 ) | ||||||
临床4期 | 203 | 壓網醖醖艱齋醖齋膚觸(餘餘憲艱觸鹽衊獵齋膚) = 鑰鏇鹹鬱遞獵糧廠簾構 糧製選範網簾餘夢獵憲 (願壓鹽範繭鹽構廠糧襯 ) | - | 2008-06-01 | |||
壓網醖醖艱齋醖齋膚觸(餘餘憲艱觸鹽衊獵齋膚) = 廠願鏇願夢壓鬱網窪選 糧製選範網簾餘夢獵憲 (願壓鹽範繭鹽構廠糧襯 ) |
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